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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF4A All Species: 26.67
Human Site: Y51 Identified Species: 39.11
UniProt: O95239 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95239 NP_036442.3 1232 139881 Y51 G T D K S F T Y D F V F D P S
Chimpanzee Pan troglodytes XP_518055 1227 139177 Y51 G T D K S F T Y D F V F D P C
Rhesus Macaque Macaca mulatta XP_001084213 1234 139742 Y51 G T D K S F T Y D F V F D P S
Dog Lupus familis XP_549061 1234 139874 Y51 G T D K S F T Y D F V F D P S
Cat Felis silvestris
Mouse Mus musculus P33174 1231 139533 Y51 G N D K S F T Y D F V F D P S
Rat Rattus norvegicus Q7M6Z5 1394 158861 F47 G R D R V F T F D F V F G K N
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q90640 1225 138905 Y51 G S D K A F T Y D Y V F D P S
Frog Xenopus laevis Q91784 1226 138905 Y50 G T E K S F T Y D Y V F D P S
Zebra Danio Brachydanio rerio Q58G59 1363 154819 C57 G N D R H F H C D F V F E D G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P46867 784 88189
Honey Bee Apis mellifera XP_395595 1064 123475 F48 N T A K A F T F N Y V F S S D
Nematode Worm Caenorhab. elegans P46873 699 78760
Sea Urchin Strong. purpuratus P46872 699 78679
Poplar Tree Populus trichocarpa XP_002302432 1055 118553 R36 V K V A L H I R P L I A D E R
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_199593 1035 116715 V34 I Q G C Q D C V T V V T G K P
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P48467 928 102392
Conservation
Percent
Protein Identity: 100 93.1 96.4 94.8 N.A. 87 27 N.A. N.A. 74.5 68.5 25.8 N.A. 26.9 36.8 27.1 27.3
Protein Similarity: 100 95.6 97.2 97 N.A. 92.7 47.6 N.A. N.A. 85.9 82.1 45.1 N.A. 41.4 56.3 38.4 39.3
P-Site Identity: 100 93.3 100 100 N.A. 93.3 53.3 N.A. N.A. 80 86.6 46.6 N.A. 0 40 0 0
P-Site Similarity: 100 93.3 100 100 N.A. 93.3 73.3 N.A. N.A. 100 100 60 N.A. 0 66.6 0 0
Percent
Protein Identity: 33.2 N.A. N.A. 32.7 N.A. 26.7
Protein Similarity: 51 N.A. N.A. 51 N.A. 44.5
P-Site Identity: 6.6 N.A. N.A. 6.6 N.A. 0
P-Site Similarity: 13.3 N.A. N.A. 6.6 N.A. 0
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 7 7 13 0 0 0 0 0 0 7 0 0 0 % A
% Cys: 0 0 0 7 0 0 7 7 0 0 0 0 0 0 7 % C
% Asp: 0 0 50 0 0 7 0 0 57 0 0 0 50 7 7 % D
% Glu: 0 0 7 0 0 0 0 0 0 0 0 0 7 7 0 % E
% Phe: 0 0 0 0 0 63 0 13 0 44 0 63 0 0 0 % F
% Gly: 57 0 7 0 0 0 0 0 0 0 0 0 13 0 7 % G
% His: 0 0 0 0 7 7 7 0 0 0 0 0 0 0 0 % H
% Ile: 7 0 0 0 0 0 7 0 0 0 7 0 0 0 0 % I
% Lys: 0 7 0 50 0 0 0 0 0 0 0 0 0 13 0 % K
% Leu: 0 0 0 0 7 0 0 0 0 7 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 7 13 0 0 0 0 0 0 7 0 0 0 0 0 7 % N
% Pro: 0 0 0 0 0 0 0 0 7 0 0 0 0 44 7 % P
% Gln: 0 7 0 0 7 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 7 0 13 0 0 0 7 0 0 0 0 0 0 7 % R
% Ser: 0 7 0 0 38 0 0 0 0 0 0 0 7 7 38 % S
% Thr: 0 38 0 0 0 0 57 0 7 0 0 7 0 0 0 % T
% Val: 7 0 7 0 7 0 0 7 0 7 69 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 44 0 19 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _